Selected Publications
Cytoplasmic division cycles without the nucleus and mitotic CDK/Cyclin complexes.
Bakshi A*, Echegaray Iturra F*, Alamban A*, Rosas-Salvans M, Dumont S, Aydogan MG+. Cell. 2023 Oct 12; doi: 10.1016/j.cell.2023.09.010.
Find it here and codes on GitHub (FRET and 3D-rendering).
Find its preprint prior to submission (2022) here.
Listen to the following invited podcast interview regarding this work by Preprints in Motion.
Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal-end.
Aydogan MG*+, Hankins LE*, Steinacker TL, Mofatteh M, Saurya S, Wainman A, Wong SS, Lu X, Zhou FY+, Raff JW+. J Cell Sci. 2022 Jun 16; doi: 10.1242/jcs.260015.
Find it here and codes on GitHub.
Find its preprint version here.
Featured by JCS as a research highlight:
An unexpected crosstalk during centriole biogenesis. JCS 2022Highlighted by JCS in a ‘First Author’ interview:
First person - Mustafa Aydogan and Laura Hankins. JCS 2022
Autonomous clocks that regulate organelle biogenesis, cytoskeletal organization, and intracellular dynamics.
Mofatteh M, Echegaray-Iturra F, Alamban A, Dalla Ricca F, Bakshi A, Aydogan MG+. Elife. 2021 Sep 29;10. doi: 10.7554/eLife.72104.
Find it here.
See the following talks at Harvard Systems Bio Theory Lunch and BPPB seminar series for a tutorial on autonomous clocks.
An autonomous oscillation times and executes centriole biogenesis.
Aydogan MG*+, Steinacker TL*, Mofatteh M, Wilmott ZM, Zhou FY, Gartenmann L, Wainman A, Saurya S, Novak ZA, Wong SS, Goriely A, Boemo MA+, Raff JW+. Cell. 2020 June 25; 181:1-16. doi: 10.1016/j.cell.2020.05.018.
Find it here and codes on GitHub (PeCoS and model).
Find its preprint version here and its highlight by the Node.
Highlighted among the “Editor’s Choice” at Science:
Ray LB. Oscillator for centriole formation. Science 2020
Evidence that a positive feedback loop drives centrosome maturation in fly embryos.
Alvarez-Rodrigo I, Steinacker TL, Saurya S, Conduit PT, Baumbach J, Novak ZA, Aydogan MG, Wainman A, Raff JW. Elife. 2019 Sep 9;8. doi: 10.7554/eLife.50130.
Find it here.
Find its preprint version here and its highlight by the Node.
A homeostatic clock sets daughter centriole size in flies.
Aydogan MG, Wainman A, Saurya S, Steinacker TL, Caballe A, Novak ZA, Baumbach J, Muschalik N, Raff JW. J Cell Biol. 2018 Apr 2;217(4):1233-1248. doi: 10.1083/jcb.201801014.
Find it here.
Highlighted among the “Editor’s Choice” at Science:
Hurtley SM. Right time, right speed, right size. Science 2018.Featured by a JCB spotlight article:
Gemble S. and Basto R. Fast and furious… or not, Plk4 dictates the pace. J Cell Biol 2018Highlighted by the following special collections of JCB: “Centrosomes and Cilia 2018”; “Cell Division, Cell Cycle, and Polarity”; “Chromosome organization and segregation”.
Drosophila Ana1 is required for centrosome assembly and centriole elongation.
Saurya S, Roque H, Novak ZA, Wainman A, Aydogan MG, Volanakis A, Sieber B, Pinto DM, Raff JW. J Cell Sci. 2016 Jul 1;129(13):2514-25. doi: 10.1242/jcs.186460.
Find it here.
For a full list of publications (including our technical and theoretical contributions), please visit here.